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Patrick Hundsdoerfer Selected Research

LCL161

10/2018Vincristine resistance in relapsed neuroblastoma can be efficiently overcome by Smac mimetic LCL161 treatment.
10/2017Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α.
11/2016Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.

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Patrick Hundsdoerfer Research Topics

Disease

12Neuroblastoma
06/2023 - 05/2012
10Neoplasms (Cancer)
01/2023 - 08/2010
4Hodgkin Disease (Hodgkin's Disease)
01/2023 - 09/2009
2Medulloblastoma
01/2023 - 11/2017
1Epstein-Barr Virus Infections
01/2023
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2021
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2021
1Starvation
01/2021
1Ewing Sarcoma (Sarcoma, Ewing)
11/2017
1Rhabdoid Tumor (Rhabdoid Tumors)
11/2017
1Congenital Diaphragmatic Hernias
01/2013
1Body Weight (Weight, Body)
09/2012
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2010
1Neoplasm Metastasis (Metastasis)
09/2009
1Osteosarcoma (Osteogenic Sarcoma)
09/2009
1Thrombosis (Thrombus)
07/2004
1Thromboembolism
10/2003

Drug/Important Bio-Agent (IBA)

3Vincristine (Oncovin)FDA LinkGeneric
06/2023 - 10/2017
3dinutuximabIBA
06/2023 - 01/2021
3AntibodiesIBA
01/2023 - 01/2021
3LCL161IBA
10/2018 - 11/2016
2Cisplatin (Platino)FDA LinkGeneric
06/2023 - 11/2017
2Immunoglobulin G (IgG)IBA
01/2022 - 01/2021
2AntigensIBA
01/2022 - 01/2021
2Proteins (Proteins, Gene)FDA Link
06/2021 - 01/2021
2Inhibitor of Apoptosis ProteinsIBA
10/2017 - 11/2016
2X-Linked Inhibitor of Apoptosis ProteinIBA
05/2012 - 08/2010
2Messenger RNA (mRNA)IBA
05/2012 - 08/2010
2Prothrombin (Factor II)IBA
07/2004 - 10/2003
1Monoclonal AntibodiesIBA
06/2023
1Etoposide (VP 16)FDA LinkGeneric
06/2023
1Vindesine (Vindesin)IBA
06/2023
1IfosfamideFDA LinkGeneric
06/2023
1Dacarbazine (DIC)FDA LinkGeneric
06/2023
1Doxorubicin (Adriamycin)FDA LinkGeneric
06/2023
1RNA (Ribonucleic Acid)IBA
01/2023
1Metabotropic Glutamate 5 ReceptorIBA
01/2023
1Circular RNAIBA
01/2023
1Programmed Cell Death 1 ReceptorIBA
01/2022
1Immune Checkpoint InhibitorsIBA
01/2022
1Immune Checkpoint ProteinsIBA
01/2022
1Semaphorin-3AIBA
06/2021
1Peptides (Polypeptides)IBA
06/2021
1NucleoproteinsIBA
06/2021
1CytokinesIBA
01/2021
1Surface Antigens (Surface Antigen)IBA
01/2021
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2021
1Immunoglobulin Fc FragmentsIBA
01/2021
1NucleotidesIBA
01/2021
1Serine (L-Serine)FDA Link
01/2021
1ProteomeIBA
01/2021
1Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)IBA
01/2021
1ceralasertibIBA
11/2017
1TransposasesIBA
11/2017
1DNA (Deoxyribonucleic Acid)IBA
11/2017
1NVP-TAE684IBA
11/2016
1DiamondIBA
01/2013
1Blood Glucose (Blood Sugar)IBA
09/2012
1LBW242IBA
05/2012
1GlucocorticoidsIBA
08/2010
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
09/2009
1factor V LeidenIBA
10/2003

Therapy/Procedure

11Therapeutics
06/2023 - 09/2009
6Drug Therapy (Chemotherapy)
06/2023 - 09/2009
2Transplantation
01/2023 - 01/2021
1Induction Chemotherapy
06/2023
1Lasers (Laser)
06/2021
1Hematopoietic Stem Cell Transplantation
01/2021
1Secondary Prevention
09/2009
1Neoadjuvant Therapy
09/2009
1Combination Drug Therapy (Combination Chemotherapy)
09/2009
1Radiotherapy
09/2009